Topical Treatments for Vitiligo

Tofacitinib 2% Topical Cream

More Information: 

https://www.cfspharmacy.pharmacy/blog/post/tofacitinib-cream-for-treatment-of-vitiligo

(see sections titled “Tofacitinib” and “Tofacitinib for Vitiligo”)

Tacrolimus Ointment 0.1%

More Information: 

https://dermnetnz.org/topics/tacrolimus

Personal Experience: 

I used these two ointments twice a day on Saturday and Sunday every week. The Tofacitinib 2% Topical Cream was compounded specially for me through a prescription from my doctor. I took equal parts of the Tofacitinib 2% Topical Cream and the Tacrolimus Ointment 0.1%, spreading a thin layer on each of my spots and rubbing the ointments in well. I only did this combination twice a day on Saturdays and Sundays, as opposed to every day of the week, because Tofacitinib is a JAK inhibitor. As a side note, although I used Tacrolimus Ointment 0.1%, children are typically prescribed tacrolimus ointment 0.03%. I used this combination of creams for a couple of years while doing phototherapy. I am not currently using these creams, as my doctor sees no need for me to continue applying them. 

Triamcinolone Acetonide Ointment USP, 0.1%

More Information: 

https://www.mayoclinic.org/diseases-conditions/vitiligo/diagnosis-treatment/drc-20355916

(see section titled “Medications”)

Personal Experience:

I applied Triamcinolone Acetonide Ointment USP, 0.1% twice a day from Monday to Friday every week. I used it while I was also using the combination of the two creams listed above. Triamcinolone is a corticosteroid, and some side effects of using corticosteroids include skin thinning or streaks appearing on skin. Thus, my doctor instructed me to use very little when rubbing it into my skin. I only spread a thin layer on my spots, and I never encountered any of these side effects. 

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